General Cell Based Assays
Cayman Chemical BIlIrubIn ConjugatesodIM100mg
A stable, water-soluble ditaurate derivative of bilirubin meant to mimic endogenous bilirubin glucuronide derivatives; exhibits anti-oxidant and antimutagenic effects
Meso Scale Discovery RPLEX HUM Thrombomodulin ASY
The R-Plex Human Thrombomodulin Assay from Meso Scale Discovery is a multiplex immunoassay that measures thrombomodulin levels in human serum plasma and cell culture supernatants This assay utilizes MSD s electrochemiluminescent detection technology and provides high sensitivity up to a 7-log dynamic range and low sample volume requirements The assay can monitor thrombomodulin levels as a biomarker of endothelial cell activation and damage It is available as a singleplex or as a multiplex with other cardiovascular disease biomarkers The R-Plex assay delivers rapid results in just 3 5 hours
Cell Signaling Technology BrdU Cell Proliferation Chemiluminescent Assay Kit 1 Kit
BrdU Cell Proliferation Chemiluminescent Assay Kit 1 Kit
Eurofins Discoverx PathHunter eXpress JAK3 Activity Assay, 2-Plate Kit. (93-0796E3CP16M)
The PathHunter eXpress U2OS JAK3 Activity Assay is a stable, engineered cell line for use in studying small molecule drug candidates targeting the JAK3 kinase domain. The cell line is engineered to express the catalytic domain from JAK3 fused to the cytokine receptor binding domain (CRBD) of JAK2. The cells co-express an Enzyme Acceptor (EA) tagged SH2 domain and a ProLink (PK) tagged Cytokine receptor. The CRBD is designed to bind the CTK catalytic domain to the PRLR-PK. Activation of the PRLR-PK induces receptor phosphorylation by the JAK3 catalytic domain. This leads to SH2-EA recruitment and production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human & Mouse Total CDK2 Detection Kit, 500 Assay Points
HTRF Human & Mouse Total CDK2 Detection Kit, 500 Assay Points
Eurofins Discoverx PathHunter eXpress YES1 Activity Assay, 2-Plate Kit. (93-0883E3CP16M)
The PathHunter eXpress YES Activity Assay is a stable, engineered cell line for use in studying small molecule drug candidates targeting the YES kinase domain. The cell line is engineered to express the catalytic domain from YES fused to the cytokine receptor binding domain (CRBD) of JAK2. The cells co-express an Enzyme Acceptor (EA) tagged SH2 domain and a ProLink (PK) tagged Cytokine receptor. The CRBD is designed to bind the CTK catalytic domain to the GHR-PK. Activation of the GHR-PK induces receptor phosphorylation by the YES catalytic domain. This leads to SH2-EA recruitment and production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress ErbB2-ErbB3 Functional Assay, 10pl Kit. (93-0535E3CP16L)
The PathHunter eXpress ErbB2-ErbB3 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated ErbB2 and ErbB3 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged ErbB2 and an EA-tagged SH2 domain protein. It also overexpresses an untagged coreceptor, ErbB3 Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-ACC (Ser79) Detection Kit, 50,000 Assay Points
HTRF Human & Mouse Phospho-ACC (Ser79) Detection Kit, 50,000 Assay Points
Abcam Senescence Detection Kit
Senescence Detection Kit
The product is subject to the following: Abcam Restricted Use Statement